KlaAtlas ยท Dataset details
PXD039257
The characterization of protein lactylation in relation to cardiac metabolic reprogramming in neonatal mouse hearts
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3,562
Reidentified Kla sites
1,097
Reidentified Kla proteins
3
Raw MS files
Dataset overview
Dataset accession
Repository
PRIDE
Publication
UniProt taxonomy ID
10090
Sample category
Tissue
Tissue / cell type
Neonatal C57BL/6J mouse whole-heart tissue; WT1-WT3 ages unresolved
Experimental condition / comparison
Study profiles postnatal P1, P5 and P7 hearts.
Experimental information
Acquisition workflow
TIMS-DDA
MS platform
Bruker TIMS
Quantification strategy
Label-free
Kla enrichment method
Pan-antibody-based PTM peptide enrichment with pre-washed antibody beads
Enrichment reagent supplier
PTM Bio
Reagent catalogue information
Not specified in accessible enrichment protocol
Data access
MaxQuant parameter files
PXD039257_mqpar.xml
Raw MS file information
3 processed acquisition files.
Original raw data may be accessed
through the source repository.
Show raw MS file names (3 files)
- ED204LPLa_WT1_Slot2-19_1_16420.d
- ED204LPLa_WT2_Slot2-21_1_16424.d
- ED204LPLa_WT3_Slot2-23_1_16428.d
Metadata sources
DOI: 10.1016/j.jgg.2024.02.009
PRIDE PXD039257
Evidence E01-E03
PRIDE PXD039257
Evidence E01-E03
Dataset notes
Sample information and limitations
Three selected WT1-WT3 acquisitions. Accessible preprint states each sample pooled 16 P1 hearts, 8 P5 hearts or 6 P7 hearts. Whether WT1-WT3 denote ages or independent pools is not documented in a verified RAW key; pooled hearts do not each constitute independent MS replicates.
Experimental metadata notes
Study profiles postnatal P1, P5 and P7 hearts. The selected WT1/WT2/WT3 files cannot be assigned to these ages from the accessible annotation.