KlaAtlas ยท Dataset details

PXD041277

Global profiling of protein lactylation in Caenorhabditis elegans

Caenorhabditis elegans iProX 2023/10
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2,434
Reidentified Kla sites
609
Reidentified Kla proteins
18
Raw MS files

Dataset overview

Dataset accession
PXD041277
Repository
iProX
Publication
37847886
UniProt taxonomy ID
6239
Sample category
Animal model
Tissue / cell type
Whole adult wild-type N2 Caenorhabditis elegans.
Experimental condition / comparison
Baseline global lactylome under normal physiological conditions; no experimental treatment/control contrast.

Experimental information

Acquisition workflow
FAIMS
MS platform
Orbitrap
Quantification strategy
Label-free
Kla enrichment method
Lactylated-peptide enrichment using lactylated resin (antibody resin)
Enrichment reagent supplier
PTM Bio / Hangzhou Jingjie Biotechnology Co., Ltd.
Reagent catalogue information
PTM-1404

Data access

MaxQuant parameter files
PXD041277_mqpar.xml
Download XML
Raw MS file information
18 processed acquisition files. Original raw data may be accessed through the source repository.
View in PRIDE
Show raw MS file names (18 files)
  • BE168PI_Lac09_Fr1_FS_-40v.raw
  • BE168PI_Lac09_Fr1_FS_-55v.raw
  • BE168PI_Lac09_Fr2_FS_-40v.raw
  • BE168PI_Lac09_Fr2_FS_-55v.raw
  • BE168PI_Lac09_Fr3_FS_-40v.raw
  • BE168PI_Lac09_Fr3_FS_-55v.raw
  • BE168PI_Lac13_Fr1_FS_-40v.raw
  • BE168PI_Lac13_Fr1_FS_-55v.raw
  • BE168PI_Lac13_Fr2_FS_-40v.raw
  • BE168PI_Lac13_Fr2_FS_-55v.raw
  • BE168PI_Lac13_Fr3_FS_-40v.raw
  • BE168PI_Lac13_Fr3_FS_-55v.raw
  • BE168PI_Lac17_Fr1_FS_-40v.raw
  • BE168PI_Lac17_Fr1_FS_-55v.raw
  • BE168PI_Lac17_Fr2_FS_-40v.raw
  • BE168PI_Lac17_Fr2_FS_-55v.raw
  • BE168PI_Lac17_Fr3_FS_-40v.raw
  • BE168PI_Lac17_Fr3_FS_-55v.raw
Metadata sources
https://doi.org/10.1002/pmic.202300185
https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD041277
Abstract; ProteomeXchange dataset description
Dataset notes
Sample information and limitations Three biological replicates (Lac09, Lac13, Lac17). Each has three fractions (Fr1-Fr3) with two FS acquisition settings (-40v, -55v), yielding 18 selected files. Fractions and paired acquisition settings are not additional biological replicates.