KlaAtlas ยท Dataset details

PXD050470

Global Profiling of Protein Lactylation in Human Hippocampi

Homo sapiens iProX 2024/12
Back to datasets
3,912
Reidentified Kla sites
1,219
Reidentified Kla proteins
9
Raw MS files

Dataset overview

Dataset accession
PXD050470
Repository
iProX
Publication
39610256
UniProt taxonomy ID
9606
Sample category
Tissue
Tissue / cell type
Human hippocampal tissue from the National Developmental and Functional Human Brain Bank; three biological tissue samples under normal physiological conditions.
Experimental condition / comparison
Baseline physiological hippocampus lactylome atlas; no disease/treatment comparison in the selected files.

Experimental information

Acquisition workflow
Standard
MS platform
Orbitrap
Quantification strategy
Label-free
Kla enrichment method
Pre-washed antibody-bead enrichment of lactylated peptides
Enrichment reagent supplier
Not specified in accessible enrichment protocol
Reagent catalogue information
Not specified in accessible enrichment protocol

Data access

MaxQuant parameter files
PXD050470_mqpar.xml
Download XML
Raw MS file information
9 processed acquisition files. Original raw data may be accessed through the source repository.
View in PRIDE
Show raw MS file names (9 files)
  • XA02614PILa_H187_Fr1.raw
  • XA02614PILa_H187_Fr2.raw
  • XA02614PILa_H187_Fr3.raw
  • XA02614PILaR1_H072_Fr1.raw
  • XA02614PILaR1_H072_Fr2.raw
  • XA02614PILaR1_H072_Fr3.raw
  • XA02614PILaR1_H081_Fr1.raw
  • XA02614PILaR1_H081_Fr2.raw
  • XA02614PILaR1_H081_Fr3.raw
Metadata sources
https://doi.org/10.1002/prca.202400061
https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD050470
Abstract; ProteomeXchange dataset description
Dataset notes
Sample information and limitations 3 biological human hippocampal tissue samples (H187, H072, H081), 3 fractions each (Fr1-3), total 9 RAWs. Baseline physiological atlas, no treatment comparison. WARNING: mqpar experiment labels are cyclically shifted relative to filename donor codes (H187->H072, H072->H081, H081->H187); preserve filename identities. Donor Table S1 unavailable.