KlaAtlas ยท Dataset details
PXD050752
Comparative Analysis of Post-Translational Modifications of Human Serum Albumin Derived from Human Plasma and Recombinant Sources in China
Back to datasets
11
Reidentified Kla sites
8
Reidentified Kla proteins
2
Raw MS files
Dataset overview
Dataset accession
Repository
PRIDE
Publication
UniProt taxonomy ID
9606
Sample category
Body fluid
Tissue / cell type
Commercial human serum albumin preparations: recombinant human serum albumin (rHSA) versus plasma-derived human serum albumin (pHSA). These are purified protein products, not tissue/cell samples.
Experimental condition / comparison
CZ = rHSA; RY = pHSA.
Experimental information
Acquisition workflow
TIMS-DDA
MS platform
Bruker TIMS
Quantification strategy
Label-free
Kla enrichment method
Anti-lactyllysine antibody-resin enrichment of lactylated peptides in a multi-PTM workflow
Enrichment reagent supplier
PTM Bio, Hangzhou, China
Reagent catalogue information
PTM-1404
Data access
MaxQuant parameter files
PXD050752_mqpar.xml
Raw MS file information
2 processed acquisition files.
Original raw data may be accessed
through the source repository.
Show raw MS file names (2 files)
- XA00584LPLa_CZ_Slot1-50_1_24745.d
- XA00584LPLa_RY_Slot1-51_1_24747.d
Metadata sources
https://doi.org/10.24976/discov.med.202436184.98
https://www.ebi.ac.uk/pride/archive/projects/PXD050752
PRIDE project description; sample protocol: Modification enrichment
https://www.ebi.ac.uk/pride/archive/projects/PXD050752
PRIDE project description; sample protocol: Modification enrichment
Dataset notes
Sample information and limitations
CZ=rHSA and RY=pHSA (explicit Figure 3 key); 1 selected TIMS-DDA lactylation acquisition/category, fraction=1. Commercial HSA preparations; exact product/lot composition, pooling and independent preparation n are unreported. Study-wide 6 pHSA + 2 rHSA products do not establish n for the selected 2 RAWs.
Experimental metadata notes
CZ = rHSA; RY = pHSA. Product-source comparison. The full paper studies six plasma-derived manufacturer products plus yeast- and rice-derived recombinant products, but their contribution to the two selected MS preparations is unspecified.